FACTORS FOR COAGULATION ABNORMALITIES DURING EXPERIMENTAL ACUTE PANCREATITIS
نویسندگان
چکیده
منابع مشابه
Coagulation Abnormalities in Acute Pancreatitis
Acute pancreatitis (AP) is a potentially lethal disorder with no specific medical treatment. AP is characterized by a spectrum of symptoms, ranging from a local inflammatory process to the more severe form (acute necrotizing pancreatitis) which is associated with a systemic inflammatory response and a mortality rate of 27-45%. A number of risk factors have been identified for AP including alcoh...
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Although microcirculatory disturbances play pivotal role in the pathomechanism of acute pancreatitis (AP), very few papers can be found which had been tested any of hemorheological parameters. The aim of our study was to analyze the hemorheological changes in cerulein-induced experimental acute pancreatitis in rat in two doses (5 and 10 μg/kg, s.c.). Male and female rats were subjected to Contr...
متن کاملPancreatic and pulmonary mast cells activation during experimental acute pancreatitis.
AIM To study the activation of pancreatic and pulmonary mast cells and the effect of mast cell inhibition on the activation of peritoneal and alveolar macrophages during acute pancreatitis. METHODS Pancreatitis was induced by intraductal infusion of 5% sodium taurodeoxycholate in rats. The mast cell inhibitor cromolyn was administered intraperitoneally (i.p.) 30 min before pancreatitis induct...
متن کاملPathobiology of experimental acute pancreatitis.
Pancreatic duct obstruction, even in the absence of biliary obstruction and/or bile reflux into the pancreatic duct, can trigger acute hemorrhagic necrotizing pancreatitis. The earliest changes are seen within acinar cells. Early derangements in acinar cell biology include inhibition of digestive enzyme secretion and the co-localization of lysosomal hydrolases with digestive enzyme zymogens. Un...
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mechanism behind this apparent thalidomide-induced hyperkalaemia remains unclear. Therefore, the authors recommend caution when thalidomide is used in patients with moderate to severe renal failure (serum creatinine >300mmol/l) or in patients on dialysis. To go a step further, we think that thalidomide should in all cases be started at a dosage that should not exceed 100mg/day. It is also impor...
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ژورنال
عنوان ژورنال: The Japanese Journal of Gastroenterological Surgery
سال: 1978
ISSN: 0386-9768,1348-9372
DOI: 10.5833/jjgs.11.829